No sabemos qué hay detrás, pero podemos darnos el gusto de llenarlo de pintadas. Blog sobre Ciencia, Tecnología y Política que, como luz y materia tras el Muro, son casi la misma cosa.
Inicio > Historias > Un nuevo (y extraño) proyecto literario personal
> Un nuevo (y extraño) proyecto literario personal <
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What is fentanyl?
Pharmaceutical fentanyl is a synthetic opioid pain reliever, approved for treating severe pain, typically advanced cancer pain.1 It is 50 to 100 times more potent than morphine. It is prescribed in the form of transdermal patches or lozenges and can be diverted for misuse and abuse in the United States.
However, most recent cases of fentanyl-related harm, overdose, and death in the U.S. are linked to illegally made fentanyl.2 It is sold through illegal drug markets for its heroin-like effect. It is often mixed with heroin and/or cocaine as a combination product—with or without the user’s knowledge—to increase its euphoric effects.
Learn More: Fentanyl Data
Illicitly-made fentanyl use is on the rise
Overdose deaths involving synthetic opioids other than methadone, which includes fentanyl, increased almost 47% from 2016 to 2017.3 Roughly 28,400 people died from overdoses involving synthetic opioids other than methadone in 2017.4
Reports from law enforcement indicate that much of the synthetic opioid overdose increase may be due to illegally or illicitly made fentanyl. According to data from the National Forensic Laboratory Information System, confiscations, or seizures, of fentanyl increased by nearly 7 fold from 2012 to 2014. There were 4,585 fentanyl confiscations in 2014.5 This suggests that the sharp rise in fentanyl-related deaths may be due to increased availability of illegally made, non-pharmaceutical fentanyl, and not prescribed fentanyl.
The number of states reporting 20 or more fentanyl confiscations every six months is increasing. From July to December 2014, 18 states reported 20 or more fentanyl drug confiscations (See Figure 1). By comparison, six states reported 20 or more fentanyl drug confiscations from July to December 2013.
What is fentanyl?
Fentanyl is part of a group of drugs known as opioids. Opioids interact with opioid receptors in the brain and elicit a range of responses within the body; from feelings of pain relief, to relaxation, pleasure and contentment.
It is prescribed in the event of chronic, severe pain as a result of cancer, nerve damage, back injury, major trauma and surgery.1 In Australia, fentanyl is a schedule 8 drug.2 It is about 80 to 100 times stronger than morphine.3
What it looks like
Fentanyl is available in many forms. Pharmaceutical fentanyl is used for managing acute or chronic pain. Illicit fentanyl can be manufactured for use in the illegal drug market.
Medicinal fentanyl comes in a number of different forms and strengths including:
transdermal patches (Durogesic® and generic versions)
lozenges/lollipops (Actiq®)
intravenous injection (Sublimaze®).
Illicit use
Some people use fentanyl illegally by extracting the fentanyl from the patch and injecting it. This is very risky as it is extremely hard to judge a dose size.
Fentanyl can be ‘diverted’. Diversion occurs when medication that is prescribed by a medical professional, is not used as directed, or is given or sold to a third party.
Prescribed fentanyl can be 'diverted' when:
individuals obtain medication without a prescription from another doctor through their profession (e.g. healthcare professionals)
individuals use their own prescribed medication recreationally
individuals use medication prescribed to another person.
Fentanyl is sometimes mixed with other drugs to increase potency. Illicitly manufactured fentanyl can be:
a stand alone product
a low cost additive to increase the potency of other illicit drugs such as heroin
sold as counterfeit medicines (such as oxycodone®).
Effects of fentanyl
There is no safe level of drug use. Use of any drug always carries some risk. It’s important to be careful when taking any type of drug.
Fentanyl affects everyone differently, based on:
size, weight and health
whether the person is used to taking it
whether other drugs are taken around the same time
the amount taken
the strength of the drug (varies between patches).
You may experience:
relief from pain
nausea, vomiting
constipation and/or diarrohea
reduced appetite
wind, indigestion, cramps
drowsiness, confusion
weakness or fatigue
dizziness
euphoria
headache
incoherent or slurred speech
impaired balance
slow pulse and lowered blood pressure
rash (inflammation, itch, swelling at patch site).1
Overdose
If the dose is too high, you might overdose. Call an ambulance straight away by dialling triple zero (000) if you have any of these symptoms (ambulance officers do not have to involve the police):
chest pain
slowed breathing
bluish lips and complexion
seizure
passing out
coma
death.1,4
Naloxone (also known as Narcan®) reverses the effects of opiates (including fentanyl), in the case of an overdose. Naloxone can be injected intravenously (into a vein) or intramuscularly (into a muscle) by medical professionals, such as paramedics. It can also be administered by family and friends of people who use opiates. Speak with your chemist or pharmacist for more information.
Naloxone information video
If injecting drugs there is an increased risk of:
tetanus.
infection.
vein damage.
If sharing needles there is an increased risk of:
hepatitis B.
hepatitis C.
HIV and AIDS.
Long term effects
Regular use of fentanyl may cause:
mood instability
reduced libido
constipation
menstrual problems
respiratory impairment.3
Using fentanyl with other drugs
The effects of taking fentanyl with other drugs – including over-the-counter or prescribed medications – can be unpredictable and dangerous and could cause:
Fentanyl + alcohol: adds to adverse effects and may increase the risk of respiratory depression.
Fentanyl + MAOI anti-depressants: may result in severe unpredictable reactions.
Fentanyl + benzodiazepines: may add to the sedative effects and diminished breathing.1
Withdrawal
Giving up fentanyl after using it for a long time is challenging because the body has to get used to functioning without it. Withdrawal symptoms usually start within 12 hours after the last dose and can last for about a week – days 1 to 3 will be the worst. These symptoms can include:
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